William A. Wallace, MD FACS

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BOTOX® – Xeomin – Wrinkle Relaxer – Fleming Island, FL*

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Wrinkle relaxers, such as BOTOX and Xeomin, have transformed the facial rejuvenation market for men and women seeking wrinkle treatment without undergoing surgery. These products (known as neuromodulators) decrease the visual appearance of fine lines and wrinkles in areas on the face that show expression, such as the forehead and around the eyes. Neuromodulators use botulinum toxin that temporarily relaxes the muscles under the skin so that the surface appears smooth and younger. While each brand essentially does the same thing and produces a similar result, they work differently for different people.

During the consultation with Fleming Island plastic surgeon Dr. William Wallace or our Nurse Practitioner, Maria Rafael, each product can be discussed so that the right one is chosen to meet your aesthetic goal. BOTOX and/or Xeomin cosmetic procedures are performed approximately 6 million times every year and offer amazing results, temporarily eliminating wrinkles along the forehead, eyes, and mouth so that you can have smoother, younger-looking skin.

What they treat

Both BOTOX and Xeomin are effective treatments to help diminish and eliminate:

  • Forehead lines and wrinkles
  • Vertical frown lines between the brows (glabella)
  • Crow's feet
  • Medical issues, such as excessive sweating

product facts


  • FDA approved in 2002
  • Medication: Onobotulinum toxin A
  • Expected results: On average, within 5 – 7 days


  • FDA approved in 2010
  • Medication: Incobotulinum toxin A
  • Expected results: On average, within 7 – 10 days

Which one is best?

All of the wrinkle relaxer treatments on the market today serve a specific purpose, and each does it well, depending on the patient and their precise needs. With that said, BOTOX continues to be the gold standard wrinkle relaxer treatment and leads the market with millions of injections given each year. It’s common for practitioners to use more than one product in a session. For example, some patients react better to BOTOX to treat forehead lines and Xeomin to treat Crow’s feet. Every patient is different, and therefore, we offer two options in neuromodulators to best suite you.

Administering BOTOX/Xeomin

BOTOX and/or Xeomin is administered during an in-office appointment that typically takes about 30 minutes. The depth, length, quantity, and location of wrinkles vary for each patient. Therefore, the injection treatment, including the dosage and injection location, is tailored during the procedure. Patients will be marked for the specific areas on the face that are going to be treated. The injection is given through a syringe to localized areas on the face. Patients will feel a small prick as the needle inserts through the skin, but any pain or discomfort is controlled with a cold compress.

What to Expect

Immediately following a series of BOTOX and/or Xeomin injections, there will be some mild swelling and redness at the injection site. This will subside a few hours after the procedure. Patients can resume their normal activities immediately, but exercise should be avoided for a few hours. It is also recommended that patients keep their head elevated for the first 8 – 10 hours. Results following BOTOX and/or Xeomin will become apparent within 4 – 7 days. About a week after treatment, patients will notice an inability to fully move portions of their forehead. With limited movement, wrinkles will cease to appear. The result is skin that appears smooth and soft.

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Average Cost  
$265 - $500
Recovery Time  
No Downtime
Average Procedure Time  
30-45 Minutes
Procedure Recovery Location  
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Botox & Xeomin FAQs

Is It Safe?

BOTOX and/or Xeomin is approved by the Food and Drug Administration (FDA) and has a long, safe history. It is administered in over 75 countries and consistently ranks as the most popular cosmetic procedure in America. However, even with its popularity, BOTOX and/or Xeomin is a drug and should only be administered by a qualified medical practitioner. Individuals who receive injections by someone inexperienced run the added risk of bruising, overmedicating, and ultimately, obtaining an undesirable result. 

Comparable Medication?

In 2009, BOTOX gained competition when Dysport (abobotulinumtoxinA) was developed, approved by the FDA, and made available to the general public. Both drugs are used to relax the facial muscles that cause wrinkles and frown lines. Some practices lean toward BOTOX to address forehead lines while considering Xeomin or Dysport for Crow’s feet. There has been much debate as to which drug is superior. Both have their advantages. Some distinct differences can be discussed during your consultation.  

Botox/Xeomin or Filler?

Injectable fillers, such as Restylane and Juvéderm, help decrease wrinkles by adding volume to certain facial structures, which creates the appearance of smooth skin. BOTOX and/or Xeomin, which temporarily freezes the underlying muscle, offers a similar result with a different approach. A skilled practitioner will be able to determine if a filler material or a product, like BOTOX and/or Xeomin, would garner the best results.  

Best Age?

Individuals who wish to soften and decrease facial lines and wrinkles may be candidates for BOTOX and/or Xeomin. The most common age to receive BOTOX and/or Xeomin injections is between 30 – 55. However, it is also common for patients younger to receive injections as this treatment is also considered a preventive for aging.

Long Lasting?

BOTOX and/or Xeomin is not a permanent fix. Results will last for several months, sometimes longer, but they will not last forever. Qualified injectors will tell you there is good news and bad news when it comes to BOTOX and/or Xeomin. The good news is that if you are not happy with your results, the results will only last a few months. Likewise, the bad news is that if you love your results (which most people do), the results will only last a few months. Regardless, many patients recognize even the temporary results are worth feeling and looking younger. 

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*Individual results are not guaranteed and may vary from person to person. Images may contain models.